The histopathological diagnosis of donovanosis.

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The histopathological diagnosis of donovanosis.

The role of histopathology in the diagnosis of donovanosis was assessed in 42 patients. There was heavy infiltration of the dermis with plasma and mononuclear cells but with few lymphocytes and neutrophils. The epidermis contained focal collections of polymorphoneuclear leucocytes. Endothelial proliferation and dilation of dermal blood vessels was striking. Intracellular and extracellular Donov...

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The diagnosis and treatment of donovanosis (granuloma inguinale).

Donovanosis is a predominantly tropical cause of genital ulcer occurring chiefly in small endemic foci in all continents except Europe. Diagnosis requires the careful collection, staining and examination of smears or biopsies of characteristic genital and, occasionally, extragenital lesions for demonstration of the pathognomonic Donovan bodies (Calymmatobacterium granulomatis) within histiocyte...

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TROPICAL MEDICINE SERIES Donovanosis

Donovanosis, a chronic cause of genital ulceration, has recently been the subject of renewed interest after a long period of relative obscurity. The causative organism, Calymmatobacterium granulomatis, has been cultured for the first time in many years and a polymerase chain reaction diagnostic using a colorimetric detection system has been developed. Phylogenetic analysis confirms close simila...

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ژورنال

عنوان ژورنال: Sexually Transmitted Infections

سال: 1984

ISSN: 1368-4973

DOI: 10.1136/sti.60.1.45